The metastases spectrum of neuroendocrine neoplasms in gastrointestinal tract

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Neuroendocrine neoplasms of the gastrointestinal tract.

BACKGROUND Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are complex tumors whose incidence is rising and whose treatment requires precise classification and risk stratification. METHOD Selective review of the relevant literature, including recently published guidelines. RESULTS GEP-NENs are initially classified by their degree of histological differentiation and their graded c...

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Diagnosis and therapy of neuroendocrine neoplasms of the gastrointestinal tract

A neuroendocrine neoplasm (nen) is a tumor that originates in neuroendocrine cells capable of producing peptides or amines. neuroendocrine neoplasms of the digestive system are also referred to as gastroenteropancreatic neuroendocrine neoplasms (GeP nen) and constitute a heterogeneous group of growths originating from at least 15 types of specialized cells spread throughout the stomach, small i...

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Histopathology of gastrointestinal neuroendocrine neoplasms

Gastrointestinal neuroendocrine neoplasms (GI-NENs) arise from neuroendocrine cells distributed mainly in the mucosa and submucosa of the gastrointestinal tract. In 2010, the World Health Organization (WHO) classification of NENs of the digestive system was changed, categorizing these tumors as grade 1 neuroendocrine tumor (NET), grade-2NET, neuroendocrine carcinoma (large- or small-cell type),...

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The surgical spectrum of pulmonary neuroendocrine neoplasms.

OBJECTIVES The purpose of this study is to review our experience with the spectrum of neuroendocrine neoplasms of the lung with emphasis on the histopathologic classification and surgical therapy of each class of neoplasm. DESIGN This retrospective review covers the entire spectrum of neuroendocrine neoplasms of the lung over an 11-year period (January 1985 to December 1995) in a university h...

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Neuroendocrine Tumors of the Gastrointestinal Tract.

Gastrointestinal neuroendocrine tumours are classified as functioning or non-functioning according to the presence or absence of a clinically evident hypersecretion syndrome. In foregut tumours the presence of autonomous hormone secretion and the respective hypersecretion syndrome indicate functionality. Abdominal ultrasound (US), computed tomography (CT), magnetic resonance tomography (MRT) an...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2017

ISSN: 0923-7534

DOI: 10.1093/annonc/mdx660.055